2-ETHOXYPHENYL ISOTHIOCYANATE
2-ETHOXYPHENYL ISOTHIOCYANATE
CAS: 23163-84-0
Molecular Formula: C9H9NOS
2-ETHOXYPHENYL ISOTHIOCYANATE - Names and Identifiers
2-ETHOXYPHENYL ISOTHIOCYANATE - Physico-chemical Properties
| Molecular Formula | C9H9NOS |
| Molar Mass | 179.24 |
| Density | 1.14 |
| Boling Point | 223 °C |
| Specific Gravity | 1.14 |
| Storage Condition | Keep Cold |
| Sensitive | Moisture Sensitive/Lachrymatory |
| Use | Use 2-ethoxyphenyl isothiocyanates are isothiocyanates which are important functional substances in natural products and pharmaceutically active compounds. Isothiocyanates are a class of compounds with the general formula of R-N = C = S. They are important organic synthesis compounds and have been widely used in mineral processing, pharmaceuticals, pesticides and dyes. |
2-ETHOXYPHENYL ISOTHIOCYANATE - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Toxic/Corrosive/Lachrymatory/Moisture Sensitive |
| Hazard Class | KEEP COLD, LACHRYMAT |
2-ETHOXYPHENYL ISOTHIOCYANATE - Upstream Downstream Industry
| Raw Materials | Chloroform Thiophosgene o-Phenetidine |
2-ETHOXYPHENYL ISOTHIOCYANATE - Nature
| boiling point | 223 °C |
| density | 1.14 |
| storage conditions | Keep Cold |
| Specific gravity | 1.14 |
| sensitivity | Moisture Sensitive/Lachrymatory |
Last Update：2024-04-10 22:29:15
2-ETHOXYPHENYL ISOTHIOCYANATE - Security information
| dangerous goods mark | C,T,Xi |
| hazard category code | 20/21/22-36/37/38-36 |
| safety instructions | 26-36/37/39 |
| Hazard Note | Toxic/Corrosive/Lachrymatory/Moisture Sensitive |
| HazardClass | KEEP COLD, LACHRYMATOR, TOXIC |
Last Update：2024-04-10 22:29:15
2-ETHOXYPHENYL ISOTHIOCYANATE - Reference Information
| use | 2-ethoxyphenyl isothiocyanate is an isothiocyanate compound, which is a very important functional substance in natural products and pharmaceutically active compounds. Isothiocyanate compounds are a class of compounds with the general structure of R-N = C = S. They are an important medium in organic synthesis and are widely used in mineral processing, medicine, pesticides and dyes. |
| preparation | 4-ethoxyaniline (2.19mol) and 309.2g triethylamine (3.06mol) are placed in a 5000mL three-mouth round bottom flask, 1000mL ethyl acetate is added, cooled in an ice bath and stirred mechanically. When the temperature of the mixed solution drops to 0 ℃ ~ 5 ℃, 299.2g CS2(3.93mol) is slowly dropped by a constant pressure drop funnel, and the temperature of the reaction solution is controlled below 30 ℃ by magnetic stirring while dropping. After dropping, magnetic stirring at room temperature (10-30 degree range) for one hour; At this temperature, 299.2g CS2(3.93mol) and DMAP catalyst were added to the reaction solution, and the reaction was stirred at 30±2.5 ℃ for 1.5h. After the reaction is over, the reaction liquid is washed twice with an acid solution. The total acid consumed by the washing is 1.5 times that of triethylamine, and then washed with saturated salt water until neutral. The organic phase is concentrated by rotary evaporation to obtain 2-ethoxyphenyl isothiocyanic acid. |
Last Update：2024-04-10 22:29:15
2-ETHOXYPHENYL ISOTHIOCYANATE - Preparation
4-ethoxyaniline (2.19mol) and 309.2g triethylamine (3.06mol) were placed in a 5000mL three-mouth round bottom flask, 1000mL ethyl acetate was added, cooled in an ice bath and stirred mechanically. When the temperature of the mixed solution drops to 0 ℃ ~ 5 ℃, 299.2g CS2(3.93mol) is slowly dropped by a constant pressure drop funnel, and the temperature of the reaction solution is controlled below 30 ℃ while dropping and stirring. After dropping, magnetic stirring at room temperature (10-30 degree range) for one hour; At this temperature, 299.2g CS2(3.93mol) and DMAP catalyst were added to the reaction solution, and the reaction was stirred at 30±2.5 ℃ for 1.5h. After the reaction is over, the reaction liquid is washed twice with an acid solution, and the total acid consumed by the washing is 1.5 times that of triethylamine, and then washed with saturated salt water until neutral. The organic phase was concentrated by rotary evaporation to obtain 2-ethoxyphenylisothiocyanic acid.
Last Update：2024-04-10 22:29:15
Supplier List
Product Name: 2-ETHOXYPHENYL ISOTHIOCYANATE Visit Supplier Webpage Request for quotation
CAS: 23163-84-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 23163-84-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: 2-ETHOXYPHENYLISOTHIOCYANATE Request for quotationCAS: 23163-84-0
Tel: +86 021-37285211
Email: info@yudiaochem.com
Mobile: +86 18964703211
QQ: 122752498
Wechat: yudiaochem
Product Name: 2-ETHOXYPHENYL ISOTHIOCYANATE Visit Supplier Webpage Request for quotation
CAS: 23163-84-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 23163-84-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: 2-ETHOXYPHENYLISOTHIOCYANATE Request for quotationCAS: 23163-84-0
Tel: +86 021-37285211
Email: info@yudiaochem.com
Mobile: +86 18964703211
QQ: 122752498
Wechat: yudiaochem
View History
Raw Materials for 2-ETHOXYPHENYL ISOTHIOCYANATE